Sun exposure, worry about tanning and pigmentation? Check out this anti-photoaging solution!

2023.09.13

Whether you're out for leisure or commuting, don't take sun protection lightly! We not only need to shield ourselves from tanning but also steer clear of the threat of photoaging. Research has shown that 80% of skin aging is attributed to photoaging [1]. Photoaging is a major culprit in skin aging. When our skin is excessively exposed to UVA, UVB, and blue light, it undergoes a series of torment: tanning, sunburn, redness, and the emergence of pigmentation issues. What's even worse is the production of a surplus of free radicals in the body and the occurrence of inflammatory reactions.

Today, we'd like to introduce to you the "activation of the endogenous antioxidant switch, Nrf2." Nrf2 is helping us combat reactive oxygen species produced by factors such as ultraviolet rays, fighting against photoaging.

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Nrf2 target has been widely studied in the field of dermatology. Research indicates that Nrf2 is a crucial regulatory transcription factor that plays a key role in maintaining the balance of oxidation-reduction processes within cells and in responding to oxidative stress.

When cells are stimulated by reactive oxygen species (ROS), Keap1 releases Nrf2, which then enters the cell nucleus, and identifies and initiates downstream gene expression. Nrf2-regulated downstream target proteins include phase II metabolic enzymes, antioxidant protease, anti-inflammatory factors, proteasomes/molecular chaperones, and phase III metabolic enzymes.

The activation of Nrf2 can be achieved through various pathways, including oxidative stress, activation of intracellular signaling pathways, and the influence of chemical substances. Activating Nrf2 can promote the expression of the skin cell's antioxidant enzyme systems, such as superoxide dismutase and glutathione peroxidase, thereby enhancing the cell's antioxidant capacity. Additionally, research has found that Nrf2 activation plays a crucial role in regulating skin health and inflammation responses.

Activating Nrf2's Number One Assistant - Biobloom™ ME-2 Lactobacillus Ferment

Mechanism of Action

Enhances Nrf2 expression, activates the body's antioxidant pathways, and reduces oxidative stress caused by excessive ROS free radicals.

Product Highlights

Developed in collaboration with the Innovation Center on Probiotics Science and Technology of Jiangnan University, scientifically selected strains, and highly efficient fermentation, activate the body's own antioxidant pathways, and offer gentle and effective anti-aging benefits through probiotics.

Product Benefits

Alleviates skin oxidative damage, tightens and brightens the skin, reduces pigment deposition, and helps brighten the skin after sun exposure.

 

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Activating Nrf2's Number Two Assistant -Ergothioneine

Mechanism of Action

By inducing the activity of Nrf2 within cells and binding with Antioxidant Response Elements (ARE), it promotes downstream gene expression of antioxidant enzymes, enhancing the cell's resistance to photooxidation while inhibiting cell apoptosis caused by UVA stimulation.

Product Highlights

Bloomage Biotech has launched three specifications of Ergothioneine products, each with distinct advantages in terms of technology, efficacy, and concept.

Product Benefits

Exceptionally potent antioxidant properties.

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